Problem with quest expert-master promote ( Esse + Alchem)

... I can't take quest Master Essencetapping from NPC Cornelius( My point 499/499 ) .. and can't take Expert Alchemy ( My point 441/449 ) quest too ... what happend?
Please Tell me how i can take that ?

 

Next time use the search button. Read

Your point is 441 / 449, You need 449 to upgrade. Raise alchemy to 449. How? You need to craft something level 410 or higher to get to 449. You can only get 41 levels above the level of the design so 410 will get you (410 + 41) 451 max, after that.. craft a design of a higher level. 420p 430p 440p etc.